Endocrine Abstracts

Introduction: Lymphocytic hypophysitis (LH) is most likely of autoimmune origin, as it is associated with other autoimmune diseases in 20 to 25% of cases, with the most common being lymphocytic thyroiditis. It is common in young women in late pregnancy or postpartum. Diabetes insipidus (DI) occurs in approximately 35% of patients with LH. To link DI to LH, we investigated the clinical, biological, and radiological characteristics of patients with DI.Pati...

Background and Aims: The Rotterdam criteria are the most accepted criteria for the diagnosis of polycystic ovary syndrome (PCOS). The aim of this research work is to study the quality of life of Tunisian and French women with PCOS according to their marital status.Methods: A cross-sectional study involved 172 women with PCOS. Data collection was based on telephone interviews with tunisian patients who were diagnosed with PCOS based on rotterdam criteria ...

Background and Aims: Polycystic ovary syndrome (PCOS) may be the most common endocrine disorder in women of reproductive age. Most research findings suggest that PCOS is associated with eating disorders (ED). The aim of this research work is to study the eating disorders in women with PCOS.Methods: A cross-sectional study involved 172 women, 101 of them are Tunisian and 71 are French. Data collection was based on telephone interviews with Tunisian patien...

Introduction: Couple’s infertility is a major public health problem. Its prevalence is estimated at 15%. In half of the cases, this infertility is of male origin. Different etiologies may be involved, among which genetic abnormalities of the Y chromosome. In this context, we report the cases of two patients with a structural abnormality of the Y chromosome responsible for the abnormalities of spermatogenesisCase Description: The first 26-year-old ca...

Background and Aims: Polycystic ovary syndrome (PCOS) may be the most common endocrine disorder in women of reproductive age. The Rotterdam criteria are the most accepted criteria for its diagnosis. The aim of this study is to study the predictors of quality of life in patients with PCOS according to nationality.Methods: A cross-sectional study involved 172 women, 101 of them Tunisian and 71 French. Data collection was based on telephone interviews with ...

Background and aims: Lower urinary tract (LUT) symptoms are one of the most common complications related to autonomous diabetic neuropathy. It is responsible for several dysfunctions due to distended bladder with a high risk of contracting retention. The current survey aims to assess the clinical manifestations of neurogenic bladder dysfunction (NBD) and determine its prevalence in patients with type 2 diabetes (T2DM).Patients and method: We conducted a ...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is an inherited syndrome characterized mainly by the association of: Primary hyperparathyroidism (PHP), gastro-entero-pancreatic tumors (GEP) and pituitary tumors. The aim of our work is to specify the particularities of PHP in MEN1 among Tunisian population.Patients & Methods: It is a retrospective descriptive study of 7 cases of MEN1, including 3 familial cases, during a 28-year period.<p...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare hereditary syndrome that should be considered when different endocrine tumors are associated in an individual or familial context. We report the observation of a Tunisian family, two sisters and a brother.Observations: Patient1: a 31 years old female, followed for multinodular goiter, was hospitalized for a left maxillary tumefaction associated with headache and blurred vision. Investigat...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a genetic disease that predisposes to the development of both hyperplastic and tumorous lesions of the endocrine glands, in particular parathyroid, pancreatic and pituitary. Thus we report our case.Observation: An 18-year-old male patient was hospitalized for severe hypoglycemia mistakenly treated as epileptic seizures. The etiological investigation concluded to a benign multiple insulinoma, con...

Introduction: Gayet Wernicke’s encephalopathy (GWE) is a severe encephalopathy secondary to acute thiamine (vitamin B1) deficiency which may lead to severe sequelae or death if the diagnosis is delayed. We report the first case in the literature of an association between GWE and primary hyperparathyroidism (PHP) in a man.Observation: He was a 57 years old man, with a personal history of hypertension and primary infertility, who presented with incoer...